Brucella melitensis Methionyl-tRNA-Synthetase (MetRS), a Potential Drug Target for Brucellosis

We investigated Brucella melitensis methionyl-tRNA-synthetase (BmMetRS) with molecular, structural and phenotypic methods to learn if BmMetRS is a promising target for brucellosis drug development. Recombinant BmMetRS was expressed, purified from wild type Brucella melitensis biovar Abortus 2308 str...

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Detalles Bibliográficos
Autores principales: Ojo, Kayode K., Ranade, Ranae M., Zhang, Zhongsheng, Dranow, David M., Myers, Janette B., Choi, Ryan, Nakazawa Hewitt, Steve, Edwards, Thomas E., Davies, Douglas R., Lorimer, Donald, Boyle, Stephen M., Barrett, Lynn K., Buckner, Frederick S., Fan, Erkang, Van Voorhis, Wesley C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976878/
https://www.ncbi.nlm.nih.gov/pubmed/27500735
http://dx.doi.org/10.1371/journal.pone.0160350

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