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Differential Assembly of Catalytic Interactions within the Conserved Active Sites of Two Ribozymes
Molecular recognition is central to biology and a critical aspect of RNA function. Yet structured RNAs typically lack the preorganization needed for strong binding and precise positioning. A striking example is the group I ribozyme from Tetrahymena, which binds its guanosine substrate (G) orders of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976970/ https://www.ncbi.nlm.nih.gov/pubmed/27501145 http://dx.doi.org/10.1371/journal.pone.0160457 |