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Combined GSTM1-Null, GSTT1-Active, GSTA1 Low-Activity and GSTP1-Variant Genotype Is Associated with Increased Risk of Clear Cell Renal Cell Carcinoma
The aim of this study was to evaluate specific glutathione S-transferase (GST) gene variants as determinants of risk in patients with clear cell renal cell carcinoma (cRCC), independently or simultaneously with established RCC risk factors, as well as to discern whether phenotype changes reflect gen...
Autores principales: | Coric, Vesna M., Simic, Tatjana P., Pekmezovic, Tatjana D., Basta-Jovanovic, Gordana M., Savic Radojevic, Ana R., Radojevic-Skodric, Sanja M., Matic, Marija G., Dragicevic, Dejan P., Radic, Tanja M., Bogdanovic, Ljiljana M., Dzamic, Zoran M., Pljesa-Ercegovac, Marija S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4976979/ https://www.ncbi.nlm.nih.gov/pubmed/27500405 http://dx.doi.org/10.1371/journal.pone.0160570 |
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