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Ischemia/reperfusion injury resistance in hibernators is more than an effect of reduced body temperature or winter season

Hibernating mammals are resistant to injury following cardiac arrest. The basis of this protection has been proposed to be due to their ability to lower body temperature or metabolic rate in a seasonally-dependent manner. However, recent studies have shown that neither reduced body temperature nor h...

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Detalles Bibliográficos
Autores principales: Bogren, Lori K, Drew, Kelly L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977161/
https://www.ncbi.nlm.nih.gov/pubmed/27583285
http://dx.doi.org/10.4161/temp.29761
Descripción
Sumario:Hibernating mammals are resistant to injury following cardiac arrest. The basis of this protection has been proposed to be due to their ability to lower body temperature or metabolic rate in a seasonally-dependent manner. However, recent studies have shown that neither reduced body temperature nor hibernation season are components this protection.