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Mitochondrial reactive oxygen species regulate the strength of inhibitory GABA-mediated synaptic transmission

Neuronal communication imposes a heavy metabolic burden in maintaining ionic gradients essential for action potential firing and synaptic signaling. Although cellular metabolism is known to regulate excitatory neurotransmission, it is still unclear whether the brain’s energy supply affects inhibitor...

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Detalles Bibliográficos
Autores principales: Accardi, Michael V., Daniels, Bryan A., Brown, Patricia M.G.E., Fritschy, Jean-Marc, Tyagarajan, Shiva K., Bowie, Derek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977183/
https://www.ncbi.nlm.nih.gov/pubmed/24430741
http://dx.doi.org/10.1038/ncomms4168