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Stability of Programmable Shunt Valve Settings with Simultaneous Use of the Optune Transducer Array: A Case Report

The Optune® transducer array (Novocure Ltd., Haifa, Israel) is an FDA-approved noninvasive regional therapy that aims to inhibit the growth of glioblastoma multiforme (GBM) cells via utilization of alternating electric fields. Some patients with GBM may develop hydrocephalus and benefit from subsequ...

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Detalles Bibliográficos
Autores principales: Chan, Andrew K, Birk, Harjus S, Winkler, Ethan A, Viner, Jennifer A, Taylor, Jennie W, McDermott, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977218/
https://www.ncbi.nlm.nih.gov/pubmed/27551653
http://dx.doi.org/10.7759/cureus.675
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author Chan, Andrew K
Birk, Harjus S
Winkler, Ethan A
Viner, Jennifer A
Taylor, Jennie W
McDermott, Michael W.
author_facet Chan, Andrew K
Birk, Harjus S
Winkler, Ethan A
Viner, Jennifer A
Taylor, Jennie W
McDermott, Michael W.
author_sort Chan, Andrew K
collection PubMed
description The Optune® transducer array (Novocure Ltd., Haifa, Israel) is an FDA-approved noninvasive regional therapy that aims to inhibit the growth of glioblastoma multiforme (GBM) cells via utilization of alternating electric fields. Some patients with GBM may develop hydrocephalus and benefit from subsequent shunt placement, but special attention must be paid to patients in whom programmable valves are utilized, given the potential effect of the magnetic fields on valve settings. We present the first case report illustrating the stability of programmable shunt valve settings in a neurosurgical patient undergoing therapy with the Optune device. In this study, shunt valve settings were stable over a period of five days despite Optune therapy. This is reassuring for patients with GBM who require simultaneous treatment with both the Optune device and a programmable shunt system.
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spelling pubmed-49772182016-08-22 Stability of Programmable Shunt Valve Settings with Simultaneous Use of the Optune Transducer Array: A Case Report Chan, Andrew K Birk, Harjus S Winkler, Ethan A Viner, Jennifer A Taylor, Jennie W McDermott, Michael W. Cureus Neurosurgery The Optune® transducer array (Novocure Ltd., Haifa, Israel) is an FDA-approved noninvasive regional therapy that aims to inhibit the growth of glioblastoma multiforme (GBM) cells via utilization of alternating electric fields. Some patients with GBM may develop hydrocephalus and benefit from subsequent shunt placement, but special attention must be paid to patients in whom programmable valves are utilized, given the potential effect of the magnetic fields on valve settings. We present the first case report illustrating the stability of programmable shunt valve settings in a neurosurgical patient undergoing therapy with the Optune device. In this study, shunt valve settings were stable over a period of five days despite Optune therapy. This is reassuring for patients with GBM who require simultaneous treatment with both the Optune device and a programmable shunt system. Cureus 2016-07-07 /pmc/articles/PMC4977218/ /pubmed/27551653 http://dx.doi.org/10.7759/cureus.675 Text en Copyright © 2016, Chan et al. http://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Neurosurgery
Chan, Andrew K
Birk, Harjus S
Winkler, Ethan A
Viner, Jennifer A
Taylor, Jennie W
McDermott, Michael W.
Stability of Programmable Shunt Valve Settings with Simultaneous Use of the Optune Transducer Array: A Case Report
title Stability of Programmable Shunt Valve Settings with Simultaneous Use of the Optune Transducer Array: A Case Report
title_full Stability of Programmable Shunt Valve Settings with Simultaneous Use of the Optune Transducer Array: A Case Report
title_fullStr Stability of Programmable Shunt Valve Settings with Simultaneous Use of the Optune Transducer Array: A Case Report
title_full_unstemmed Stability of Programmable Shunt Valve Settings with Simultaneous Use of the Optune Transducer Array: A Case Report
title_short Stability of Programmable Shunt Valve Settings with Simultaneous Use of the Optune Transducer Array: A Case Report
title_sort stability of programmable shunt valve settings with simultaneous use of the optune transducer array: a case report
topic Neurosurgery
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977218/
https://www.ncbi.nlm.nih.gov/pubmed/27551653
http://dx.doi.org/10.7759/cureus.675
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