Cargando…

mRNA Cap Methylation in Pluripotency and Differentiation

The mRNA cap recruits factors essential for transcript processing and translation initiation. We report that regulated mRNA cap methylation is a feature of embryonic stem cell (ESC) differentiation. Expression of the mRNA cap methyltransferase activating subunit RAM is elevated in ESCs, resulting in...

Descripción completa

Detalles Bibliográficos
Autores principales:	Grasso, Laura, Suska, Olga, Davidson, Lindsay, Gonatopoulos-Pournatzis, Thomas, Williamson, Ritchie, Wasmus, Lize, Wiedlich, Simone, Peggie, Mark, Stavridis, Marios P., Cowling, Victoria H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977272/ https://www.ncbi.nlm.nih.gov/pubmed/27452456 http://dx.doi.org/10.1016/j.celrep.2016.06.089

Ejemplares similares

RAM/Fam103a1 Is Required for mRNA Cap Methylation
por: Gonatopoulos-Pournatzis, Thomas, et al.
Publicado: (2011)

Cap-binding complex (CBC)
por: Gonatopoulos-Pournatzis, Thomas, et al.
Publicado: (2013)

RAM function is dependent on Kapβ2-mediated nuclear entry
por: Gonatopoulos-Pournatzis, Thomas, et al.
Publicado: (2014)

mRNA Cap Methyltransferase, RNMT-RAM, Promotes RNA Pol II-Dependent Transcription
por: Varshney, Dhaval, et al.
Publicado: (2018)

Regulation of mRNA cap methylation
por: Cowling, Victoria H.
Publicado: (2009)

Myc and mRNA capping()
por: Dunn, Sianadh, et al.
Publicado: (2015)

CAPAM: The mRNA Cap Adenosine N6-Methyltransferase
por: Cowling, Victoria H.
Publicado: (2019)

mRNA cap regulation in mammalian cell function and fate()
por: Galloway, Alison, et al.
Publicado: (2019)

c-Myc co-ordinates mRNA cap methylation and ribosomal RNA production
por: Dunn, Sianadh, et al.
Publicado: (2017)

Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors
por: Cole, Michael D., et al.
Publicado: (2009)

CAP-MAP: cap analysis protocol with minimal analyte processing, a rapid and sensitive approach to analysing mRNA cap structures
por: Galloway, Alison, et al.
Publicado: (2020)

c-Myc deregulation induces mRNA capping enzyme dependency
por: Lombardi, Olivia, et al.
Publicado: (2016)

CDK1-Cyclin B1 Activates RNMT, Coordinating mRNA Cap Methylation with G1 Phase Transcription
por: Aregger, Michael, et al.
Publicado: (2016)

Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation
por: Galloway, Alison, et al.
Publicado: (2021)

Oncogenic PIK3CA mutations increase dependency on the mRNA cap methyltransferase, RNMT, in breast cancer cells
por: Dunn, Sianadh, et al.
Publicado: (2019)

A novel RNA pol II CTD interaction site on the mRNA capping enzyme is essential for its allosteric activation
por: Bage, Marcus G, et al.
Publicado: (2021)

Widespread intron retention in mammals functionally tunes transcriptomes
por: Braunschweig, Ulrich, et al.
Publicado: (2014)

Mechanism of allosteric activation of human mRNA cap methyltransferase (RNMT) by RAM: insights from accelerated molecular dynamics simulations
por: Bueren-Calabuig, Juan A, et al.
Publicado: (2019)

E2F1-dependent methyl cap formation requires RNA pol II phosphorylation
por: Aregger, Michael, et al.
Publicado: (2012)

CMTR1 is recruited to transcription start sites and promotes ribosomal protein and histone gene expression in embryonic stem cells
por: Liang, Shang, et al.
Publicado: (2022)

Synthetic mRNA capping
por: Muttach, Fabian, et al.
Publicado: (2017)

Cap-Independent Circular mRNA Translation Efficiency
por: Deviatkin, Andrei A., et al.
Publicado: (2023)

In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation
por: Bouvet, Mickaël, et al.
Publicado: (2010)

The mRNA cap methyltransferase gene TbCMT1 is not essential in vitro but is a virulence factor in vivo for bloodstream form Trypanosoma brucei
por: Kelner, Anna, et al.
Publicado: (2018)

Human cap methyltransferase (RNMT) N-terminal non-catalytic domain mediates recruitment to transcription initiation sites
por: Aregger, Michael, et al.
Publicado: (2013)

The RNA cap methyltransferases RNMT and CMTR1 co-ordinate gene expression during neural differentiation
por: Liang, Shang, et al.
Publicado: (2023)

Correction: In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation
por: Bouvet, Mickaël, et al.
Publicado: (2010)

mRNA capping: biological functions and applications
por: Ramanathan, Anand, et al.
Publicado: (2016)

Interplay of mRNA capping and transcription machineries
por: Kachaev, Zaur M., et al.
Publicado: (2020)

To cap it all off, again: dynamic capping and recapping of coding and non-coding RNAs to control transcript fate and biological activity
por: Borden, KLB, et al.
Publicado: (2021)

Cap analogs with a hydrophobic photocleavable tag enable facile purification of fully capped mRNA with various cap structures
por: Inagaki, Masahito, et al.
Publicado: (2023)

mRNA ageing shapes the Cap2 methylome in mammalian mRNA
por: Despic, Vladimir, et al.
Publicado: (2023)

DHX15 regulates CMTR1-dependent gene expression and cell proliferation
por: Inesta-Vaquera, Francisco, et al.
Publicado: (2018)

Metabolic Alterations Caused by Defective Cardiolipin Remodeling in Inherited Cardiomyopathies
por: Wasmus, Christina, et al.
Publicado: (2020)

Cap-Independent mRNA Translation in Germ Cells
por: Keiper, Brett D.
Publicado: (2019)

Conventional and unconventional mechanisms for capping viral mRNA
por: Decroly, Etienne, et al.
Publicado: (2011)

mRNA Cap-1 Methyltransferase in the SARS Genome
por: von Grotthuss, Marcin, et al.
Publicado: (2003)

Viral and cellular mRNA capping: Past and prospects
por: Furuichi, Yasuhiro, et al.
Publicado: (2000)

The Differential Formation of the LINC-Mediated Perinuclear Actin Cap in Pluripotent and Somatic Cells
por: Khatau, Shyam B., et al.
Publicado: (2012)

Arabidopsis DXO1 activates RNMT1 to methylate the mRNA guanosine cap
por: Xiao, Chen, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_oglg6m1k6914cppqm3u295a995