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Stochastic anomaly of methylome but persistent SRY hypermethylation in disorder of sex development in canine somatic cell nuclear transfer

Somatic cell nuclear transfer (SCNT) provides an excellent model for studying epigenomic reprogramming during mammalian development. We mapped the whole genome and whole methylome for potential anomalies of mutations or epimutations in SCNT-generated dogs with XY chromosomal sex but complete gonadal...

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Detalles Bibliográficos
Autores principales:	Jeong, Young-Hee, Lu, Hanlin, Park, Chi-Hun, Li, Meiyan, Luo, Huijuan, Kim, Joung Joo, Liu, Siyang, Ko, Kyeong Hee, Huang, Shujia, Hwang, In Sung, Kang, Mi Na, Gong, Desheng, Park, Kang Bae, Choi, Eun Ji, Park, Jung Hyun, Jeong, Yeon Woo, Moon, Changjong, Hyun, Sang-Hwan, Kim, Nam Hyung, Jeung, Eui-Bae, Yang, Huanming, Hwang, Woo Suk, Gao, Fei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977463/ https://www.ncbi.nlm.nih.gov/pubmed/27501986 http://dx.doi.org/10.1038/srep31088

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