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Repositioning organohalogen drugs: a case study for identification of potent B-Raf V600E inhibitors via docking and bioassay
Drug repositioning has been attracting increasingly attention for its advantages of reducing costs and risks. Statistics showed that around one quarter of the marketed drugs are organohalogens. However, no study has been reported, to the best of our knowledge, to aim at efficiently repositioning org...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977465/ https://www.ncbi.nlm.nih.gov/pubmed/27501852 http://dx.doi.org/10.1038/srep31074 |