Opening up the blackbox: an interpretable deep neural network-based classifier for cell-type specific enhancer predictions

BACKGROUND: Gene expression is mediated by specialized cis-regulatory modules (CRMs), the most prominent of which are called enhancers. Early experiments indicated that enhancers located far from the gene promoters are often responsible for mediating gene transcription. Knowing their properties, reg...

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Detalles Bibliográficos
Autores principales: Kim, Seong Gon, Theera-Ampornpunt, Nawanol, Fang, Chih-Hao, Harwani, Mrudul, Grama, Ananth, Chaterji, Somali
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977478/
https://www.ncbi.nlm.nih.gov/pubmed/27490187
http://dx.doi.org/10.1186/s12918-016-0302-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977478/
https://www.ncbi.nlm.nih.gov/pubmed/27490187
http://dx.doi.org/10.1186/s12918-016-0302-3

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