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Opening up the blackbox: an interpretable deep neural network-based classifier for cell-type specific enhancer predictions
BACKGROUND: Gene expression is mediated by specialized cis-regulatory modules (CRMs), the most prominent of which are called enhancers. Early experiments indicated that enhancers located far from the gene promoters are often responsible for mediating gene transcription. Knowing their properties, reg...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977478/ https://www.ncbi.nlm.nih.gov/pubmed/27490187 http://dx.doi.org/10.1186/s12918-016-0302-3 |