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Identifying the topology of signaling networks from partial RNAi data
BACKGROUND: Methods for inferring signaling networks using single gene knockdown RNAi experiments and reference networks have been proposed in recent years. These methods assume that RNAi information is available for all the genes in the signal transduction pathway, i.e., complete. This assumption d...
Autores principales: | Ren, Yuanfang, Wang, Qiyao, Hasan, Md Mahmudul, Ay, Ahmet, Kahveci, Tamer |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977480/ https://www.ncbi.nlm.nih.gov/pubmed/27490106 http://dx.doi.org/10.1186/s12918-016-0301-4 |
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