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Glucose level determines excitatory or inhibitory effects of adiponectin on arcuate POMC neuron activity and feeding

Adiponectin regulates glucose and lipid metabolism, acting against metabolic syndrome and atherosclerosis. Accumulating evidence suggest that adiponectin acts on the brain including hypothalamic arcuate nucleus (ARC), where proopiomelanocortin (POMC) neurons play key roles in feeding regulation. Sev...

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Detalles Bibliográficos
Autores principales: Suyama, Shigetomo, Maekawa, Fumihiko, Maejima, Yuko, Kubota, Naoto, Kadowaki, Takashi, Yada, Toshihiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977585/
https://www.ncbi.nlm.nih.gov/pubmed/27503800
http://dx.doi.org/10.1038/srep30796