Cargando…
Glucose level determines excitatory or inhibitory effects of adiponectin on arcuate POMC neuron activity and feeding
Adiponectin regulates glucose and lipid metabolism, acting against metabolic syndrome and atherosclerosis. Accumulating evidence suggest that adiponectin acts on the brain including hypothalamic arcuate nucleus (ARC), where proopiomelanocortin (POMC) neurons play key roles in feeding regulation. Sev...
Autores principales: | Suyama, Shigetomo, Maekawa, Fumihiko, Maejima, Yuko, Kubota, Naoto, Kadowaki, Takashi, Yada, Toshihiko |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977585/ https://www.ncbi.nlm.nih.gov/pubmed/27503800 http://dx.doi.org/10.1038/srep30796 |
Ejemplares similares
-
Adiponectin potentiates the acute effects of leptin in arcuate Pomc neurons
por: Sun, Jia, et al.
Publicado: (2016) -
TRPV1-Mediated Sensing of Sodium and Osmotic Pressure in POMC Neurons in the Arcuate Nucleus of the Hypothalamus
por: Zhang, Boyang, et al.
Publicado: (2022) -
Optogenetic activation of leptin- and glucose-regulated GABAergic neurons in dorsomedial hypothalamus promotes food intake via inhibitory synaptic transmission to paraventricular nucleus of hypothalamus
por: Otgon-Uul, Zesemdorj, et al.
Publicado: (2016) -
Insulin suppresses ghrelin-induced calcium signaling in neuropeptide Y neurons of the hypothalamic arcuate nucleus
por: Maejima, Yuko, et al.
Publicado: (2011) -
Endothelial HIF-1α Enables Hypothalamic Glucose Uptake to Drive POMC Neurons
por: Varela, Luis, et al.
Publicado: (2017)