Cargando…
HDAC 1 and 6 modulate cell invasion and migration in clear cell renal cell carcinoma
BACKGROUND: Class I histone deacetylases (HDACs) have been reported to be overexpressed in clear cell renal cell carcinoma (ccRCC), whereas the expression of class II HDACs is unknown. METHODS: Four isogenic cell lines C2/C2VHL and 786-O/786-OVHL with differential VHL expression are used in our stud...
Autores principales: | Ramakrishnan, Swathi, Ku, ShengYu, Ciamporcero, Eric, Miles, Kiersten Marie, Attwood, Kris, Chintala, Sreenivasulu, Shen, Li, Ellis, Leigh, Sotomayor, Paula, Swetzig, Wendy, Huang, Ray, Conroy, Dylan, Orillion, Ashley, Das, Gokul, Pili, Roberto |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977667/ https://www.ncbi.nlm.nih.gov/pubmed/27506904 http://dx.doi.org/10.1186/s12885-016-2604-7 |
Ejemplares similares
-
YAP activation protects urothelial cell carcinoma from treatment-induced DNA damage
por: Ciamporcero, Eric, et al.
Publicado: (2015) -
Dll4 Blockade Potentiates the Anti-Tumor Effects of VEGF Inhibition in Renal Cell Carcinoma Patient-Derived Xenografts
por: Miles, Kiersten Marie, et al.
Publicado: (2014) -
Combinatorial antitumor effect of HDACs and the PI3K-Akt-mTOR pathway inhibition in a Pten deficient model of prostate cancer
por: Ellis, Leigh, et al.
Publicado: (2013) -
Class I Histone Deacetylase Inhibitor Entinostat Suppresses Regulatory T Cells and Enhances Immunotherapies in Renal and Prostate Cancer Models
por: Shen, Li, et al.
Publicado: (2012) -
Combination of the histone deacetylase inhibitor vorinostat with bevacizumab in patients with clear-cell renal cell carcinoma: a multicentre, single-arm phase I/II clinical trial
por: Pili, Roberto, et al.
Publicado: (2017)