Aquaporin 4-specific T cells and NMO-IgG cause primary retinal damage in experimental NMO/SD

Neuromyelitis optica/spectrum disorder (NMO/SD) is a severe, inflammatory disease of the central nervous system (CNS). In the majority of patients, it is associated with the presence of pathogenic serum autoantibodies (the so-called NMO-IgGs) directed against the water channel aquaporin 4 (AQP4), an...

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Detalles Bibliográficos
Autores principales: Zeka, Bleranda, Hastermann, Maria, Kaufmann, Nathalie, Schanda, Kathrin, Pende, Marko, Misu, Tatsuro, Rommer, Paulus, Fujihara, Kazuo, Nakashima, Ichiro, Dahle, Charlotte, Leutmezer, Fritz, Reindl, Markus, Lassmann, Hans, Bradl, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977668/
https://www.ncbi.nlm.nih.gov/pubmed/27503347
http://dx.doi.org/10.1186/s40478-016-0355-y

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