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A tissue-specific protein purification approach in Caenorhabditis elegans identifies novel interaction partners of DLG-1/Discs large

BACKGROUND: Affinity purification followed by mass spectrometry (AP/MS) is a widely used approach to identify protein interactions and complexes. In multicellular organisms, the accurate identification of protein complexes by AP/MS is complicated by the potential heterogeneity of complexes in differ...

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Detalles Bibliográficos
Autores principales: Waaijers, Selma, Muñoz, Javier, Berends, Christian, Ramalho, João J., Goerdayal, Soenita S., Low, Teck Y., Zoumaro-Djayoon, Adja D., Hoffmann, Michael, Koorman, Thijs, Tas, Roderick P., Harterink, Martin, Seelk, Stefanie, Kerver, Jana, Hoogenraad, Casper C., Bossinger, Olaf, Tursun, Baris, van den Heuvel, Sander, Heck, Albert J. R., Boxem, Mike
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977824/
https://www.ncbi.nlm.nih.gov/pubmed/27506200
http://dx.doi.org/10.1186/s12915-016-0286-x