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Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting ‘Tefera Hailu’ memorial hospital, Sekota, Northern Ethiopia

BACKGROUND: Hepatitis B virus is one of the most causative agents of human liver disease, including acute and chronic hepatitis, cirrhosis and hepatocellular carcinoma. The disease is a great health problem worldwide, with estimated of 350 million chronically infected people. Objective: The aim of t...

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Autores principales: Gebreegziabher, Daniel, Asfeha, Gebrekidan Gebregzabher, Gebreyesus, Hagos Amare
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977854/
https://www.ncbi.nlm.nih.gov/pubmed/27503445
http://dx.doi.org/10.1186/s12879-016-1744-3
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author Gebreegziabher, Daniel
Asfeha, Gebrekidan Gebregzabher
Gebreyesus, Hagos Amare
author_facet Gebreegziabher, Daniel
Asfeha, Gebrekidan Gebregzabher
Gebreyesus, Hagos Amare
author_sort Gebreegziabher, Daniel
collection PubMed
description BACKGROUND: Hepatitis B virus is one of the most causative agents of human liver disease, including acute and chronic hepatitis, cirrhosis and hepatocellular carcinoma. The disease is a great health problem worldwide, with estimated of 350 million chronically infected people. Objective: The aim of this study was to determine the prevalence of hepatitis B virus in Tefera Hailu Memorial Hospital (THMH) for the last three years (2013, 2014, 2015) by using secondary data. METHOD: A three year retrospective record review was conducted from March 01/2015-July 30/2015. All registered data for hepatitis B virus serological screening of the specified period were included. The data were collected by predesigned data collection sheet. The sample size was calculated by simple statistical estimation to be 149 for each year. RESULT: Of 482 subjects, 215 (44.60 %) were females and 267 (55.40 %) were males. The overall prevalence of HBV was 102 (21.16 %). The positivity rate was 69 (14.31 %) in the age group between 15 and 45. There was a decrease in the prevalence of HBV from 2012 up to 2014. CONCLUSION: The seroprevalence of HBsAg was higher in males than in females and the yearly prevalence decreases from 2012–2014. But HBV infection is still a public health problem in Ethiopia. Therefore intensification of health education concerning modes of transmission and prevention of HBV, early case finding and treatment is recommended to reduce the spread of the disease.
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spelling pubmed-49778542016-08-17 Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting ‘Tefera Hailu’ memorial hospital, Sekota, Northern Ethiopia Gebreegziabher, Daniel Asfeha, Gebrekidan Gebregzabher Gebreyesus, Hagos Amare BMC Infect Dis Research Article BACKGROUND: Hepatitis B virus is one of the most causative agents of human liver disease, including acute and chronic hepatitis, cirrhosis and hepatocellular carcinoma. The disease is a great health problem worldwide, with estimated of 350 million chronically infected people. Objective: The aim of this study was to determine the prevalence of hepatitis B virus in Tefera Hailu Memorial Hospital (THMH) for the last three years (2013, 2014, 2015) by using secondary data. METHOD: A three year retrospective record review was conducted from March 01/2015-July 30/2015. All registered data for hepatitis B virus serological screening of the specified period were included. The data were collected by predesigned data collection sheet. The sample size was calculated by simple statistical estimation to be 149 for each year. RESULT: Of 482 subjects, 215 (44.60 %) were females and 267 (55.40 %) were males. The overall prevalence of HBV was 102 (21.16 %). The positivity rate was 69 (14.31 %) in the age group between 15 and 45. There was a decrease in the prevalence of HBV from 2012 up to 2014. CONCLUSION: The seroprevalence of HBsAg was higher in males than in females and the yearly prevalence decreases from 2012–2014. But HBV infection is still a public health problem in Ethiopia. Therefore intensification of health education concerning modes of transmission and prevention of HBV, early case finding and treatment is recommended to reduce the spread of the disease. BioMed Central 2016-08-08 /pmc/articles/PMC4977854/ /pubmed/27503445 http://dx.doi.org/10.1186/s12879-016-1744-3 Text en © The Author(s). 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research Article
Gebreegziabher, Daniel
Asfeha, Gebrekidan Gebregzabher
Gebreyesus, Hagos Amare
Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting ‘Tefera Hailu’ memorial hospital, Sekota, Northern Ethiopia
title Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting ‘Tefera Hailu’ memorial hospital, Sekota, Northern Ethiopia
title_full Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting ‘Tefera Hailu’ memorial hospital, Sekota, Northern Ethiopia
title_fullStr Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting ‘Tefera Hailu’ memorial hospital, Sekota, Northern Ethiopia
title_full_unstemmed Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting ‘Tefera Hailu’ memorial hospital, Sekota, Northern Ethiopia
title_short Seroprevalence of hepatitis B virus surface antigen (HBsAg) among clients visiting ‘Tefera Hailu’ memorial hospital, Sekota, Northern Ethiopia
title_sort seroprevalence of hepatitis b virus surface antigen (hbsag) among clients visiting ‘tefera hailu’ memorial hospital, sekota, northern ethiopia
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4977854/
https://www.ncbi.nlm.nih.gov/pubmed/27503445
http://dx.doi.org/10.1186/s12879-016-1744-3
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