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Phase I metabolites of mephedrone display biological activity as substrates at monoamine transporters

BACKGROUND AND PURPOSE: 4‐Methyl‐N‐methylcathinone (mephedrone) is a synthetic stimulant that acts as a substrate‐type releaser at transporters for dopamine (DAT), noradrenaline (NET) and 5‐HT (SERT). Upon systemic administration, mephedrone is metabolized to several phase I compounds: the N‐demethy...

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Detalles Bibliográficos
Autores principales:	Mayer, F P, Wimmer, L, Dillon‐Carter, O, Partilla, J S, Burchardt, N V, Mihovilovic, M D, Baumann, M H, Sitte, H H
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2016
Materias:	Research Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978154/ https://www.ncbi.nlm.nih.gov/pubmed/27391165 http://dx.doi.org/10.1111/bph.13547

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