Data on synthesis of methylene bisphosphonates and screening of their inhibitory activity towards HIV reverse transcriptase

Inorganic pyrophosphate (PPi) mimetics designed on a basis of methylenediphosphonic acid backbone are promising inhibitors of two key HIV replication enzymes, IN [1] and RT [2]. Herein, we present chemical synthesis of eleven methylenebisphosphonates (BPs) with their NMR and HRMS analysis synthesize...

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Detalles Bibliográficos
Autores principales: Yanvarev, D.V., Korovina, A.N., Usanov, N.N., Khomich, O.A., Vepsäläinen, J., Puljula, E., Kukhanova, M.K., Kochetkov, S.N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Data Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978200/
https://www.ncbi.nlm.nih.gov/pubmed/27547792
http://dx.doi.org/10.1016/j.dib.2016.07.039

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