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Enhancement of human plasma glucosylceramide assay sensitivity using delipidized plasma

Glucosylceramide (GL-1) level in human has been considered as a surrogate biomarker for enzyme replacement and substrate reduction therapies (ERT and SRT) for Gaucher and Fabry patients. Due to the high endogenous level of GL-1 in human plasma, it is difficult to achieve the analytical sensitivity o...

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Detalles Bibliográficos
Autores principales: Zheng, Kefei, Ji, Allena, Chung, Lee Lee, Culm-Merdek, Kerry, Liu, Hanlan, Richards, Susan, Sung, Crystal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978213/
https://www.ncbi.nlm.nih.gov/pubmed/27547732
http://dx.doi.org/10.1016/j.ymgmr.2016.07.004