Natural Cubic Spline Regression Modeling Followed by Dynamic Network Reconstruction for the Identification of Radiation-Sensitivity Gene Association Networks from Time-Course Transcriptome Data

Gene expression time-course experiments allow to study the dynamics of transcriptomic changes in cells exposed to different stimuli. However, most approaches for the reconstruction of gene association networks (GANs) do not propose prior-selection approaches tailored to time-course transcriptome dat...

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Detalles Bibliográficos
Autores principales: Michna, Agata, Braselmann, Herbert, Selmansberger, Martin, Dietz, Anne, Hess, Julia, Gomolka, Maria, Hornhardt, Sabine, Blüthgen, Nils, Zitzelsberger, Horst, Unger, Kristian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978405/
https://www.ncbi.nlm.nih.gov/pubmed/27505168
http://dx.doi.org/10.1371/journal.pone.0160791

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