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Genetic Barrier to Direct Acting Antivirals in HCV Sequences Deposited in the European Databank
BACKGROUND & AIMS: Development of resistance results from mutations in the viral genome, and the presence of selective drug pressure leads to the emergence of a resistant virus population. The aim of this study was to analyze the impact of genetic variability on the genetic barrier to drug resis...
Autores principales: | Kliemann, Dimas Alexandre, Tovo, Cristiane Valle, Gorini da Veiga, Ana Beatriz, Machado, André Luiz, West, John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978475/ https://www.ncbi.nlm.nih.gov/pubmed/27504952 http://dx.doi.org/10.1371/journal.pone.0159924 |
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