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Poly(I:C) Induces Human Lung Endothelial Barrier Dysfunction by Disrupting Tight Junction Expression of Claudin-5

Viral infections are often accompanied by pulmonary microvascular leakage and vascular endothelial dysfunction via mechanisms that are not completely defined. Here, we investigated the effect of the Toll-like receptor 3 (TLR3) ligand polyinosinic-polycytidylic acid [Poly(I:C)], a synthetic analog of...

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Detalles Bibliográficos
Autores principales:	Huang, Li-Yun, Stuart, Christine, Takeda, Kazuyo, D’Agnillo, Felice, Golding, Basil
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978501/ https://www.ncbi.nlm.nih.gov/pubmed/27504984 http://dx.doi.org/10.1371/journal.pone.0160875

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