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Interferon Regulatory Factor-1 Mediates Alveolar Macrophage Pyroptosis During LPS-Induced Acute Lung Injury in Mice

Previously, we demonstrated that pyroptosis in alveolar macrophages (AMs) plays an essential role in lipopolysaccharide (LPS)-induced acute lung injury. However, the underlying mechanism remains largely unclear. Here, we show that the absence of interferon regulatory factor 1 (IRF-1) in genetic knoc...

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Detalles Bibliográficos
Autores principales:	Wu, Dongdong, Pan, Pinhua, Su, Xiaoli, Zhang, Lemeng, Qin, Qingwu, Tan, Hongyi, Huang, Li, Li, Yuanyuan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Lippincott Williams & Wilkins 2016
Materias:	Basic Science Aspects
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978602/ https://www.ncbi.nlm.nih.gov/pubmed/26939040 http://dx.doi.org/10.1097/SHK.0000000000000595

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