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Spironolactone Prevents Endothelial Nitric Oxide Synthase Uncoupling and Vascular Dysfunction Induced by β-Adrenergic Overstimulation: Role of Perivascular Adipose Tissue
Sustained stimulation of β-adrenoceptors (β-ARs) and activation of renin–angiotensin–aldosterone system are common features of cardiovascular diseases with rising sympathetic activation, including essential hypertension, myocardial infarction, and heart failure. In this study, we investigated the ro...
Autores principales: | Victorio, Jamaira A., Clerici, Stefano P., Palacios, Roberto, Alonso, María J., Vassallo, Dalton V., Jaffe, Iris Z., Rossoni, Luciana V., Davel, Ana P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Lippincott, Williams & Wilkins
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978608/ https://www.ncbi.nlm.nih.gov/pubmed/27432866 http://dx.doi.org/10.1161/HYPERTENSIONAHA.116.07911 |
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