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Synaptic GluN2B/CaMKII-α Signaling Induces Synapto-Nuclear Transport of ERK and Jacob

A central pathway in synaptic plasticity couples N-Methyl-D-Aspartate-receptor (NMDAR)-signaling to the activation of extracellular signal-regulated kinases (ERKs) cascade. ERK-dependency has been demonstrated for several forms of synaptic plasticity as well as learning and memory and includes local...

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Detalles Bibliográficos
Autores principales: Melgarejo da Rosa, Michelle, Yuanxiang, PingAn, Brambilla, Riccardo, Kreutz, Michael R., Karpova, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978723/
https://www.ncbi.nlm.nih.gov/pubmed/27559307
http://dx.doi.org/10.3389/fnmol.2016.00066