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Predictive Model of Lymphocyte-Specific Protein Tyrosine Kinase (LCK) Autoregulation
Lymphocyte-specific protein tyrosine kinase (LCK) is a key activator of T cells; however, little is known about the specific autoregulatory mechanisms that control its activity. We have constructed a model of LCK autophosphorylation and phosphorylation by the regulating kinase CSK. The model was fit...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978775/ https://www.ncbi.nlm.nih.gov/pubmed/27547268 http://dx.doi.org/10.1007/s12195-016-0438-7 |