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Predictive Model of Lymphocyte-Specific Protein Tyrosine Kinase (LCK) Autoregulation

Lymphocyte-specific protein tyrosine kinase (LCK) is a key activator of T cells; however, little is known about the specific autoregulatory mechanisms that control its activity. We have constructed a model of LCK autophosphorylation and phosphorylation by the regulating kinase CSK. The model was fit...

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Detalles Bibliográficos
Autores principales:	Rohrs, Jennifer A., Wang, Pin, Finley, Stacey D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978775/ https://www.ncbi.nlm.nih.gov/pubmed/27547268 http://dx.doi.org/10.1007/s12195-016-0438-7

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