HMBA Enhances Prostratin-Induced Activation of Latent HIV-1 via Suppressing the Expression of Negative Feedback Regulator A20/TNFAIP3 in NF-κB Signaling

In the past decade, much emphasis has been put on the transcriptional activation of HIV-1, which is proposed as a promised strategy for eradicating latent HIV-1 provirus. Two drugs, prostratin and hexamethylene bisacetamide (HMBA), have shown potent effects as inducers for releasing HIV-1 latency wh...

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Detalles Bibliográficos
Autores principales: Chen, Duchu, Wang, Huiping, Aweya, Jude Juventus, Chen, Yanheng, Chen, Meihua, Wu, Xiaomeng, Chen, Xiaonan, Lu, Jing, Chen, Ruichuan, Liu, Min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978819/
https://www.ncbi.nlm.nih.gov/pubmed/27529070
http://dx.doi.org/10.1155/2016/5173205

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