Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation

To protect host against immune-mediated damage, immune responses are tightly regulated. The regulation of immune responses is mediated by various populations of mature immune cells, such as T regulatory cells and B regulatory cells, but also by immature cells of different origins. In this review, we...

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Autores principales: Vladimirovna, Irina Lyadova, Sosunova, Ekaterina, Nikolaev, Alexander, Nenasheva, Tatiana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978836/
https://www.ncbi.nlm.nih.gov/pubmed/27529074
http://dx.doi.org/10.1155/2016/7121580
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author Vladimirovna, Irina Lyadova
Sosunova, Ekaterina
Nikolaev, Alexander
Nenasheva, Tatiana
author_facet Vladimirovna, Irina Lyadova
Sosunova, Ekaterina
Nikolaev, Alexander
Nenasheva, Tatiana
author_sort Vladimirovna, Irina Lyadova
collection PubMed
description To protect host against immune-mediated damage, immune responses are tightly regulated. The regulation of immune responses is mediated by various populations of mature immune cells, such as T regulatory cells and B regulatory cells, but also by immature cells of different origins. In this review, we discuss regulatory properties and mechanisms whereby two distinct populations of immature cells, mesenchymal stem cells, and myeloid derived suppressor cells mediate immune regulation, focusing on their similarities, discrepancies, and potential clinical applications.
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spelling pubmed-49788362016-08-15 Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation Vladimirovna, Irina Lyadova Sosunova, Ekaterina Nikolaev, Alexander Nenasheva, Tatiana J Immunol Res Review Article To protect host against immune-mediated damage, immune responses are tightly regulated. The regulation of immune responses is mediated by various populations of mature immune cells, such as T regulatory cells and B regulatory cells, but also by immature cells of different origins. In this review, we discuss regulatory properties and mechanisms whereby two distinct populations of immature cells, mesenchymal stem cells, and myeloid derived suppressor cells mediate immune regulation, focusing on their similarities, discrepancies, and potential clinical applications. Hindawi Publishing Corporation 2016 2016-07-27 /pmc/articles/PMC4978836/ /pubmed/27529074 http://dx.doi.org/10.1155/2016/7121580 Text en Copyright © 2016 Irina Lyadova Vladimirovna et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Vladimirovna, Irina Lyadova
Sosunova, Ekaterina
Nikolaev, Alexander
Nenasheva, Tatiana
Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation
title Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation
title_full Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation
title_fullStr Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation
title_full_unstemmed Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation
title_short Mesenchymal Stem Cells and Myeloid Derived Suppressor Cells: Common Traits in Immune Regulation
title_sort mesenchymal stem cells and myeloid derived suppressor cells: common traits in immune regulation
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978836/
https://www.ncbi.nlm.nih.gov/pubmed/27529074
http://dx.doi.org/10.1155/2016/7121580
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