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Mutations in Dnaaf1 and Lrrc48 Cause Hydrocephalus, Laterality Defects, and Sinusitis in Mice

We have previously described a forward genetic screen in mice for abnormalities of brain development. Characterization of two hydrocephalus mutants by whole-exome sequencing after whole-genome SNP mapping revealed novel recessive mutations in Dnaaf1 and Lrrc48. Mouse mutants of these two genes have...

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Detalles Bibliográficos
Autores principales:	Ha, Seungshin, Lindsay, Anna M., Timms, Andrew E., Beier, David R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Genetics Society of America 2016
Materias:	Investigations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4978901/ https://www.ncbi.nlm.nih.gov/pubmed/27261005 http://dx.doi.org/10.1534/g3.116.030791

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