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Self-organized centripetal movement of corneal epithelium in the absence of external cues

Maintaining the structure of the cornea is essential for high-quality vision. In adult mammals, corneal epithelial cells emanate from stem cells in the limbus, driven by an unknown mechanism towards the centre of the cornea as cohesive clonal groups. Here we use complementary mathematical and biolog...

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Detalles Bibliográficos
Autores principales: Lobo, Erwin P., Delic, Naomi C., Richardson, Alex, Raviraj, Vanisri, Halliday, Gary M., Di Girolamo, Nick, Myerscough, Mary R., Lyons, J. Guy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979063/
https://www.ncbi.nlm.nih.gov/pubmed/27499113
http://dx.doi.org/10.1038/ncomms12388