β-Catenin C-terminal signals suppress p53 and are essential for artery formation

Increased activity of the tumour suppressor p53 is incompatible with embryogenesis, but how p53 is controlled is not fully understood. Differential requirements for p53 inhibitors Mdm2 and Mdm4 during development suggest that these control mechanisms are context-dependent. Artery formation requires...

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Detalles Bibliográficos
Autores principales: Riascos-Bernal, Dario F., Chinnasamy, Prameladevi, Cao, Longyue (Lily), Dunaway, Charlene M., Valenta, Tomas, Basler, Konrad, Sibinga, Nicholas E. S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979065/
https://www.ncbi.nlm.nih.gov/pubmed/27499244
http://dx.doi.org/10.1038/ncomms12389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979065/
https://www.ncbi.nlm.nih.gov/pubmed/27499244
http://dx.doi.org/10.1038/ncomms12389

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