Cargando…

β-Catenin C-terminal signals suppress p53 and are essential for artery formation

Increased activity of the tumour suppressor p53 is incompatible with embryogenesis, but how p53 is controlled is not fully understood. Differential requirements for p53 inhibitors Mdm2 and Mdm4 during development suggest that these control mechanisms are context-dependent. Artery formation requires...

Descripción completa

Detalles Bibliográficos
Autores principales:	Riascos-Bernal, Dario F., Chinnasamy, Prameladevi, Cao, Longyue (Lily), Dunaway, Charlene M., Valenta, Tomas, Basler, Konrad, Sibinga, Nicholas E. S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979065/ https://www.ncbi.nlm.nih.gov/pubmed/27499244 http://dx.doi.org/10.1038/ncomms12389

Ejemplares similares

Allograft inflammatory factor-1-like is not essential for age dependent weight gain or HFD-induced obesity and glucose insensitivity
por: Parikh, Dippal, et al.
Publicado: (2020)

Induction of interferon signaling and allograft inflammatory factor 1 in macrophages in a mouse model of breast cancer metastases
por: Zheng, Wei, et al.
Publicado: (2021)

Neutrophil extracellular traps in cardiac hypertrophy: a KLF2 perspective
por: Riascos-Bernal, Dario F., et al.
Publicado: (2022)

The Atypical Cadherin FAT1 Limits Mitochondrial Respiration and Proliferation of Vascular Smooth Muscle Cells
por: Riascos-Bernal, Dario F., et al.
Publicado: (2022)

Pax6-dependent, but β-catenin-independent, function of Bcl9 proteins in mouse lens development
por: Cantù, Claudio, et al.
Publicado: (2014)

Increased adipose catecholamine levels and protection from obesity with loss of Allograft Inflammatory Factor-1
por: Chinnasamy, Prameladevi, et al.
Publicado: (2023)

The FAT1 Cadherin Drives Vascular Smooth Muscle Cell Migration
por: Riascos-Bernal, Dario F., et al.
Publicado: (2023)

GATA3 mediates nonclassical β-catenin signaling in skeletal cell fate determination and ectopic chondrogenesis
por: Maruyama, Takamitsu, et al.
Publicado: (2022)

Distinct adhesion-independent functions of β-catenin control stage-specific sensory neurogenesis and proliferation
por: Gay, Max Hans-Peter, et al.
Publicado: (2015)

Differential regulation of β-catenin-mediated transcription via N- and C-terminal co-factors governs identity of murine intestinal epithelial stem cells
por: Borrelli, Costanza, et al.
Publicado: (2021)

Allograft inflammatory factor-1-like is a situational regulator of leptin levels, hyperphagia, and obesity
por: Parikh, Dippal, et al.
Publicado: (2022)

A novel role for the tumour suppressor Nitrilase1 modulating the Wnt/β-catenin signalling pathway
por: Mittag, Sonnhild, et al.
Publicado: (2016)

The interactions of Bcl9/Bcl9L with β-catenin and Pygopus promote breast cancer growth, invasion, and metastasis
por: Vafaizadeh, Vida, et al.
Publicado: (2021)

Perking Up Strategies to Control Restenosis
por: Riascos-Bernal, Dario F.
Publicado: (2020)

Distinct populations of crypt-associated fibroblasts act as signaling hubs to control colon homeostasis
por: Brügger, Michael David, et al.
Publicado: (2020)

Terminal differentiation of villus tip enterocytes is governed by distinct Tgfβ superfamily members
por: Berková, Linda, et al.
Publicado: (2023)

BCL9/9L-β-catenin Signaling is Associated With Poor Outcome in Colorectal Cancer
por: Moor, Andreas E., et al.
Publicado: (2015)

Protection of Armadillo/β-Catenin by Armless, a Novel Positive Regulator of Wingless Signaling
por: Reim, Gerlinde, et al.
Publicado: (2014)

Glycoprotein (GP)96 Is Essential for Maintaining Intestinal Epithelial Architecture by Supporting Its Self-Renewal Capacity
por: Häfliger, Janine, et al.
Publicado: (2022)

Mutations in Bcl9 and Pygo genes cause congenital heart defects by tissue-specific perturbation of Wnt/β-catenin signaling
por: Cantù, Claudio, et al.
Publicado: (2018)

WNT ligands control initiation and progression of human papillomavirus-driven squamous cell carcinoma
por: Zimmerli, Dario, et al.
Publicado: (2018)

Inactivation of the tumor suppressor gene Apc synergizes with H. pylori to induce DNA damage in murine gastric stem and progenitor cells
por: He, Jiazhuo, et al.
Publicado: (2023)

Wnt/ß-catenin-mediated p53 suppression is indispensable for osteogenesis of mesenchymal progenitor cells
por: Zhou, Xin, et al.
Publicado: (2021)

TBX3 acts as tissue-specific component of the Wnt/β-catenin transcriptional complex
por: Zimmerli, Dario, et al.
Publicado: (2020)

Wnt/β-Catenin Signaling Pathway Is Necessary for the Specification but Not the Maintenance of the Mouse Retinal Pigment Epithelium
por: Kim, Jong-Myeong, et al.
Publicado: (2023)

Rb and p53 Liver Functions Are Essential for Xenobiotic Metabolism and Tumor Suppression
por: Nantasanti, Sathidpak, et al.
Publicado: (2016)

Canonical Wnt/β-Catenin Signalling Is Essential for Optic Cup Formation
por: Hägglund, Anna-Carin, et al.
Publicado: (2013)

Suppression of neointima formation by targeting β-catenin/TCF pathway
por: Williams, Helen, et al.
Publicado: (2016)

Neat1 is a p53-inducible lincRNA essential for transformation suppression
por: Mello, Stephano S., et al.
Publicado: (2017)

MDMX is essential for the regulation of p53 protein levels in the absence of a functional MDM2 C-terminal tail
por: Sanford, Jack D., et al.
Publicado: (2021)

C-terminal-truncated HBV X promotes hepato-oncogenesis through inhibition of tumor-suppressive β-catenin/BAMBI signaling
por: Lee, Seok, et al.
Publicado: (2016)

RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection
por: Chapman, J. Ross, et al.
Publicado: (2013)

RIF1 Is Essential for 53BP1-Dependent Nonhomologous End Joining and Suppression of DNA Double-Strand Break Resection
por: Chapman, J. Ross, et al.
Publicado: (2021)

Triptonide Effectively Inhibits Wnt/β-Catenin Signaling via C-terminal Transactivation Domain of β-catenin
por: Chinison, Jessica, et al.
Publicado: (2016)

Suppression of Wnt/β-catenin signaling by EGF receptor is required for hair follicle development
por: Tripurani, Swamy K., et al.
Publicado: (2018)

N-terminal nesprin-2 variants regulate β-catenin signalling
por: Zhang, Qiuping, et al.
Publicado: (2016)

Connexin43 Carboxyl-Terminal Domain Directly Interacts with β-Catenin
por: Spagnol, Gaelle, et al.
Publicado: (2018)

P53 and Beta-Catenin Activity during Estrogen treatment of Osteoblasts
por: Chandar, Nalini, et al.
Publicado: (2005)

Autophagy in Endometriosis: Beta-Catenin Suppressive Role
por: Popryadukhin, A.Y., et al.
Publicado: (2020)

A C-terminally truncated form of β-catenin acts as a novel regulator of Wnt/β-catenin signaling in planarians
por: Su, Hanxia, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_aqpdi6rv87dpodheqkh80886b1