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The transposable element environment of human genes is associated with histone and expression changes in cancer
BACKGROUND: Only 2 % of the human genome code for proteins. Among the remaining 98 %, transposable elements (TEs) represent millions of sequences. TEs have an impact on genome evolution by promoting mutations. Especially, TEs possess their own regulatory sequences and can alter the expression patter...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979156/ https://www.ncbi.nlm.nih.gov/pubmed/27506777 http://dx.doi.org/10.1186/s12864-016-2970-1 |