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Why so little effort to study anti-oxidant therapy in burns?
Given that oxidative stress is an inherent response to burn injury, it is puzzling as to why investigation into anti-oxidant therapy as an adjunct to burn treatment has been limited. Both the inflammatory response and the stress response to burn injury involve oxidative stress, and there has been so...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979192/ https://www.ncbi.nlm.nih.gov/pubmed/27574696 http://dx.doi.org/10.1186/s41038-016-0056-6 |
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| author | Klein, Gordon L. |
| author_facet | Klein, Gordon L. |
| author_sort | Klein, Gordon L. |
| collection | PubMed |
| description | Given that oxidative stress is an inherent response to burn injury, it is puzzling as to why investigation into anti-oxidant therapy as an adjunct to burn treatment has been limited. Both the inflammatory response and the stress response to burn injury involve oxidative stress, and there has been some limited success in studies using gamma tocopherol and selenium to improve certain consequences of burns. Much remains to be done to investigate the number, doses and combinations of anti-oxidants, their efficacy, and limitations in improving defined outcomes after burn injury. |
| format | Online Article Text |
| id | pubmed-4979192 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2016 |
| publisher | BioMed Central |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-49791922016-08-29 Why so little effort to study anti-oxidant therapy in burns? Klein, Gordon L. Burns Trauma Commentary Given that oxidative stress is an inherent response to burn injury, it is puzzling as to why investigation into anti-oxidant therapy as an adjunct to burn treatment has been limited. Both the inflammatory response and the stress response to burn injury involve oxidative stress, and there has been some limited success in studies using gamma tocopherol and selenium to improve certain consequences of burns. Much remains to be done to investigate the number, doses and combinations of anti-oxidants, their efficacy, and limitations in improving defined outcomes after burn injury. BioMed Central 2016-08-10 /pmc/articles/PMC4979192/ /pubmed/27574696 http://dx.doi.org/10.1186/s41038-016-0056-6 Text en © The Author(s) 2016 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
| spellingShingle | Commentary Klein, Gordon L. Why so little effort to study anti-oxidant therapy in burns? |
| title | Why so little effort to study anti-oxidant therapy in burns? |
| title_full | Why so little effort to study anti-oxidant therapy in burns? |
| title_fullStr | Why so little effort to study anti-oxidant therapy in burns? |
| title_full_unstemmed | Why so little effort to study anti-oxidant therapy in burns? |
| title_short | Why so little effort to study anti-oxidant therapy in burns? |
| title_sort | why so little effort to study anti-oxidant therapy in burns? |
| topic | Commentary |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979192/ https://www.ncbi.nlm.nih.gov/pubmed/27574696 http://dx.doi.org/10.1186/s41038-016-0056-6 |
| work_keys_str_mv | AT kleingordonl whysolittleefforttostudyantioxidanttherapyinburns |