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ICOS Co-Stimulation: Friend or Foe?

Over the last 15 years, the inducible T cell co-stimulator (ICOS) has been implicated in various immune outcomes, including the induction and regulation of Th1, Th2, and Th17 immunity. In addition to its role in directing effector T cell differentiation, ICOS has also been consistently linked with t...

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Detalles Bibliográficos
Autores principales: Wikenheiser, Daniel J., Stumhofer, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979228/
https://www.ncbi.nlm.nih.gov/pubmed/27559335
http://dx.doi.org/10.3389/fimmu.2016.00304