Cargando…
Metastatic clear cell variant of renal cell carcinoma of the mandible: Review and case report
A case of metastatic renal cell carcinoma (RCC) to the mandible is reported. A 22-year-old man consulted us for hypoesthesia of the right lower lip. Panorama X-ray film showed a radiolucent lesion in the right mandibular body. A diagnosis of a metastatic tumor to the mandible from the right kidney w...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979332/ https://www.ncbi.nlm.nih.gov/pubmed/27563625 http://dx.doi.org/10.4103/2231-0746.186121 |
_version_ | 1782447305606037504 |
---|---|
author | Shah, Ajaz Jahan, Shahi Najar, Latief Hassan, Shahid Mohammad, Manzoor |
author_facet | Shah, Ajaz Jahan, Shahi Najar, Latief Hassan, Shahid Mohammad, Manzoor |
author_sort | Shah, Ajaz |
collection | PubMed |
description | A case of metastatic renal cell carcinoma (RCC) to the mandible is reported. A 22-year-old man consulted us for hypoesthesia of the right lower lip. Panorama X-ray film showed a radiolucent lesion in the right mandibular body. A diagnosis of a metastatic tumor to the mandible from the right kidney was made after evaluation by computed tomography and bone scan with Tc99 methyl diphosphonate which also revealed multiple bone metastases. Histologically diagnosis was clear cell variant of RCC. Patient has been put on radiotherapy for symptomatic treatment and a molecularly targeted drug. The therapy effectively stopped the progressive growth of oral and other metastatic lesions. The quality of life is relatively well maintained with tolerable adverse effects. The patient is still on our follow-up with an improved quality of life. |
format | Online Article Text |
id | pubmed-4979332 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2016 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-49793322016-08-25 Metastatic clear cell variant of renal cell carcinoma of the mandible: Review and case report Shah, Ajaz Jahan, Shahi Najar, Latief Hassan, Shahid Mohammad, Manzoor Ann Maxillofac Surg Case Report - Tumor A case of metastatic renal cell carcinoma (RCC) to the mandible is reported. A 22-year-old man consulted us for hypoesthesia of the right lower lip. Panorama X-ray film showed a radiolucent lesion in the right mandibular body. A diagnosis of a metastatic tumor to the mandible from the right kidney was made after evaluation by computed tomography and bone scan with Tc99 methyl diphosphonate which also revealed multiple bone metastases. Histologically diagnosis was clear cell variant of RCC. Patient has been put on radiotherapy for symptomatic treatment and a molecularly targeted drug. The therapy effectively stopped the progressive growth of oral and other metastatic lesions. The quality of life is relatively well maintained with tolerable adverse effects. The patient is still on our follow-up with an improved quality of life. Medknow Publications & Media Pvt Ltd 2016 /pmc/articles/PMC4979332/ /pubmed/27563625 http://dx.doi.org/10.4103/2231-0746.186121 Text en Copyright: © Annals of Maxillofacial Surgery http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report - Tumor Shah, Ajaz Jahan, Shahi Najar, Latief Hassan, Shahid Mohammad, Manzoor Metastatic clear cell variant of renal cell carcinoma of the mandible: Review and case report |
title | Metastatic clear cell variant of renal cell carcinoma of the mandible: Review and case report |
title_full | Metastatic clear cell variant of renal cell carcinoma of the mandible: Review and case report |
title_fullStr | Metastatic clear cell variant of renal cell carcinoma of the mandible: Review and case report |
title_full_unstemmed | Metastatic clear cell variant of renal cell carcinoma of the mandible: Review and case report |
title_short | Metastatic clear cell variant of renal cell carcinoma of the mandible: Review and case report |
title_sort | metastatic clear cell variant of renal cell carcinoma of the mandible: review and case report |
topic | Case Report - Tumor |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979332/ https://www.ncbi.nlm.nih.gov/pubmed/27563625 http://dx.doi.org/10.4103/2231-0746.186121 |
work_keys_str_mv | AT shahajaz metastaticclearcellvariantofrenalcellcarcinomaofthemandiblereviewandcasereport AT jahanshahi metastaticclearcellvariantofrenalcellcarcinomaofthemandiblereviewandcasereport AT najarlatief metastaticclearcellvariantofrenalcellcarcinomaofthemandiblereviewandcasereport AT hassanshahid metastaticclearcellvariantofrenalcellcarcinomaofthemandiblereviewandcasereport AT mohammadmanzoor metastaticclearcellvariantofrenalcellcarcinomaofthemandiblereviewandcasereport |