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αTAT1 downregulation induces mitotic catastrophe in HeLa and A549 cells
α-Tubulin acetyltransferase 1 (αTAT1) controls reversible acetylation on Lys40 of α-tubulin and modulates multiple cellular functions. αTAT1 depletion induced morphological defects of touch receptor neurons in Caenorhabditis elegans and impaired cell adhesion and contact inhibition in mouse embryoni...
Autores principales: | Chien, J-Y, Tsen, S-D, Chien, C-C, Liu, H-W, Tung, C-Y, Lin, C-H |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979442/ https://www.ncbi.nlm.nih.gov/pubmed/27551500 http://dx.doi.org/10.1038/cddiscovery.2016.6 |
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