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Inhibition of malignant thyroid carcinoma cell proliferation by Ras and galectin-3 inhibitors

Anaplastic Thyroid carcinoma is an extremely aggressive solid tumor that resists most treatments and is almost always fatal. Galectin-3 (Gal-3) is an important marker for thyroid carcinomas and a scaffold of the K-Ras protein. S-trans, transfarnesylthiosalicylic acid (FTS; Salirasib) is a Ras inhibi...

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Detalles Bibliográficos
Autores principales:	Menachem, A, Bodner, O, Pastor, J, Raz, A, Kloog, Y
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979473/ https://www.ncbi.nlm.nih.gov/pubmed/27551476 http://dx.doi.org/10.1038/cddiscovery.2015.47

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