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DIDS (4,4'-Diisothiocyanatostilbene-2,2'-disulfonate) directly inhibits caspase activity in HeLa cell lysates

Apoptosis is an important mechanism of cell demise in multicellular organisms and Cl(−) transport has an important role in the progression of the apoptotic volume decrease (AVD). DIDS (4,4'-Diisothiocyanatostilbene-2,2'-disulfonate) is one of the most commonly used Cl(−) transport inhibito...

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Detalles Bibliográficos
Autores principales:	Benítez-Rangel, E, López-Méndez, MC, García, L, Guerrero-Hernández, A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979491/ https://www.ncbi.nlm.nih.gov/pubmed/27551467 http://dx.doi.org/10.1038/cddiscovery.2015.37

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