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Pro-survival function of MEF2 in cardiomyocytes is enhanced by β-blockers
β1-Adrenergic receptor (β1-AR) stimulation increases apoptosis in cardiomyocytes through activation of cAMP/protein kinase A (PKA) signaling. The myocyte enhancer factor 2 (MEF2) proteins function as important regulators of myocardial gene expression. Previously, we reported that PKA signaling direc...
Autores principales: | Hashemi, S, Salma, J, Wales, S, McDermott, JC |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979494/ https://www.ncbi.nlm.nih.gov/pubmed/27551452 http://dx.doi.org/10.1038/cddiscovery.2015.19 |
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