Cargando…

ΔNp63α modulates histone methyl transferase SETDB1 to transcriptionally repress target genes in cancers

Detalles Bibliográficos
Autores principales:	Regina, C, Compagnone, M, Peschiaroli, A, Lena, AM, Melino, G, Candi, E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Editorial
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979509/ https://www.ncbi.nlm.nih.gov/pubmed/27551509 http://dx.doi.org/10.1038/cddiscovery.2016.15

Ejemplares similares

Setdb1, a novel interactor of ΔNp63, is involved in breast tumorigenesis
por: Regina, Carla, et al.
Publicado: (2016)

ΔNp63-Senataxin circuit controls keratinocyte differentiation by promoting the transcriptional termination of epidermal genes
por: Gatti, Veronica, et al.
Publicado: (2022)

ΔNp63 regulates the expression of hyaluronic acid-related genes in breast cancer cells
por: Gatti, Veronica, et al.
Publicado: (2018)

ΔNp63 promotes IGF1 signalling through IRS1 in squamous cell carcinoma
por: Frezza, Valentina, et al.
Publicado: (2018)

ΔNp63 in squamous cell carcinoma: defining the oncogenic routes affecting epigenetic landscape and tumour microenvironment
por: Gatti, Veronica, et al.
Publicado: (2019)

SETDB2 promoted breast cancer stem cell maintenance by interaction with and stabilization of ΔNp63α protein
por: Ying, Liu, et al.
Publicado: (2020)

Tumor suppressor WWOX binds to ΔNp63α and sensitizes cancer cells to chemotherapy
por: Salah, Z, et al.
Publicado: (2013)

ΔNp63α utilizes multiple mechanisms to repress transcription in squamous cell carcinoma cells
por: Gallant-Behm, Corrie L., et al.
Publicado: (2013)

ΔNp63α transcriptionally represses p53 target genes involved in the radiation-induced DNA damage response: ΔNp63α may cause genomic instability in epithelial stem cells
por: Kudo, Ken-ichi, et al.
Publicado: (2022)

The long non-coding RNA NEAT1 is a ΔNp63 target gene modulating epidermal differentiation
por: Fierro, Claudia, et al.
Publicado: (2023)

ΔNp63 intronic miR-944 is implicated in the ΔNp63-mediated induction of epidermal differentiation
por: Kim, Kyu-Han, et al.
Publicado: (2015)

ΔNp63α-mediated epigenetic regulation in keratinocyte senescence
por: Kuang, Linghan, et al.
Publicado: (2023)

c-Abl phosphorylation of ΔNp63α is critical for cell viability
por: Yuan, M, et al.
Publicado: (2010)

ΔNp63α and microRNAs: leveraging the epithelial-mesenchymal transition
por: Stacy, Andrew J., et al.
Publicado: (2016)

ΔNp63 drives epithelial differentiation in glioma
por: Lu, Jia‐Hao, et al.
Publicado: (2020)

ßNp63 controls cellular redox status
por: Annicchiarico-Petruzzelli, Margherita, et al.
Publicado: (2015)

Dual regulation of TERT activity through transcription and splicing by ΔNP63α
por: Vorovich, Esther, et al.
Publicado: (2008)

ΔNp63α Transcriptionally Regulates the Expression of CTEN That Is Associated with Prostate Cell Adhesion
por: Yang, Kuan, et al.
Publicado: (2016)

ΔNp63α induces the expression of FAT2 and Slug to promote tumor invasion
por: Dang, Tuyen T., et al.
Publicado: (2016)

DNA damage induces expression of WWP1 to target ΔNp63α to degradation
por: Chen, Ji, et al.
Publicado: (2017)

E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma
por: Xu, Jing, et al.
Publicado: (2021)

ΔNp63α promotes Epstein-Barr virus latency in undifferentiated epithelial cells
por: Van Sciver, Nicholas, et al.
Publicado: (2021)

ΔNp63 Is Essential for Epidermal Commitment of Embryonic Stem Cells
por: Medawar, Alain, et al.
Publicado: (2008)

ΔNp63 mediates cellular survival and metastasis in canine osteosarcoma
por: Cam, Maren, et al.
Publicado: (2016)

ΔNp63α enhances the oncogenic phenotype of osteosarcoma cells by inducing the expression of GLI2
por: Ram Kumar, Ram Mohan, et al.
Publicado: (2014)

ΔNp63α regulates Erk signaling via MKP3 to inhibit cancer metastasis
por: Bergholz, Johann, et al.
Publicado: (2012)

ΔNp63α activates CD82 metastasis suppressor to inhibit cancer cell invasion
por: Wu, J, et al.
Publicado: (2014)

Targeting of ΔNp63α by miR‐522 promotes the migration of breast epithelial cells
por: Dong, Yuanyuan, et al.
Publicado: (2021)

Correction: E47 upregulates ΔNp63α to promote growth of squamous cell carcinoma
por: Xu, Jing, et al.
Publicado: (2022)

ΔNp63α facilitates proliferation and migration, and modulates the chromatin landscape in intrahepatic cholangiocarcinoma cells
por: Peng, Anghui, et al.
Publicado: (2023)

MicroRNA-203 inhibits cell proliferation by repressing ΔNp63 expression in human esophageal squamous cell carcinoma
por: Yuan, Yang, et al.
Publicado: (2011)

A Hidden Role of the Inactivated FANCD2: Upregulating ΔNp63
por: Panneerselvam, Jayabal, et al.
Publicado: (2013)

Elevated expression of ΔNp63 in advanced esophageal squamous cell carcinoma
por: Kumakura, Yuji, et al.
Publicado: (2017)

YAP Dysregulation by Phosphorylation or ΔNp63-mediated Gene Repression Promotes Proliferation, Survival and Migration in Head and Neck Cancer Subsets
por: Ehsanian, Reza, et al.
Publicado: (2010)

ΔNp63α expression induces loss of cell adhesion in triple-negative breast cancer cells
por: Nekulova, Marta, et al.
Publicado: (2016)

Human Papilloma Virus Increases ΔNp63α Expression in Head and Neck Squamous Cell Carcinoma
por: Citro, Simona, et al.
Publicado: (2020)

SYT7 acts as an oncogene and a potential therapeutic target and was regulated by ΔNp63α in HNSCC
por: Fu, You, et al.
Publicado: (2021)

Functional antagonism between ΔNp63α and GCM1 regulates human trophoblast stemness and differentiation
por: Wang, Liang-Jie, et al.
Publicado: (2022)

ΔNp63 to TAp63 expression ratio as a potential molecular marker for cervical cancer prognosis
por: Park, Sunyoung, et al.
Publicado: (2019)

DNA Demethylation Switches Oncogenic ΔNp63 to Tumor Suppressive TAp63 in Squamous Cell Carcinoma
por: Pokorna, Zuzana, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_va9e54h05vl5lq7bfsgp1ns1gp