Mitochondrial DNA plasticity is an essential inducer of tumorigenesis

Although mitochondrial DNA has been implicated in diseases such as cancer, its role remains to be defined. Using three models of tumorigenesis, namely glioblastoma multiforme, multiple myeloma and osteosarcoma, we show that mitochondrial DNA plays defining roles at early and late tumour progression....

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Detalles Bibliográficos
Autores principales: Lee, W T Y, Cain, J E, Cuddihy, A, Johnson, J, Dickinson, A, Yeung, K-Y, Kumar, B, Johns, T G, Watkins, D N, Spencer, A, St John, J C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979526/
https://www.ncbi.nlm.nih.gov/pubmed/27551510
http://dx.doi.org/10.1038/cddiscovery.2016.16

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