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Targeting Alzheimer’s Disease Neuro-Metabolic Dysfunction with a Small Molecule Nuclear Receptor Agonist (T3D-959) Reverses Disease Pathologies

BACKGROUND: Alzheimer’s disease (AD) could be regarded as a brain form of diabetes since insulin resistance and deficiency develop early and progress with severity of neurodegeneration. Preserving insulin’s actions in the brain restores function and reduces neurodegeneration. T3D-959 is a dual nucle...

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Detalles Bibliográficos
Autores principales:	Tong, Ming, Dominguez, Cesar, Didsbury, John, de la Monte, Suzanne M
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979550/ https://www.ncbi.nlm.nih.gov/pubmed/27525190 http://dx.doi.org/10.4172/2161-0460.1000238

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