Melatonin decreases estrogen receptor binding to estrogen response elements sites on the OCT4 gene in human breast cancer stem cells

Cancer stem cells (CSCs) pose a challenge in cancer treatment, as these cells can drive tumor growth and are resistant to chemotherapy. Melatonin exerts its oncostatic effects through the estrogen receptor (ER) pathway in cancer cells, however its action in CSCs is unclear. Here, we evaluated the ef...

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Detalles Bibliográficos
Autores principales: Lopes, Juliana, Arnosti, David, Trosko, James E., Tai, Mei-Hui, Zuccari, Debora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979593/
https://www.ncbi.nlm.nih.gov/pubmed/27551335
http://dx.doi.org/10.18632/genesandcancer.107

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979593/
https://www.ncbi.nlm.nih.gov/pubmed/27551335
http://dx.doi.org/10.18632/genesandcancer.107

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