A Patient With Metastatic Sarcoma was Successfully Treated With Radiolabeled Somatostatin Analogs

We present a sarcoma patient with a tumor reduction of more than 50% in lung metastasis after 2 single courses of the investigational medical product Lutathera ((177)Lu-DOTA0-Tyr3-octreotate). She was resistant to more than 6 lines of therapy including all the available active drugs in soft tissue s...

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Autores principales: Crespo-Jara, Aurora, González Manzano, Ramón, Lopera Sierra, Maribel, Redal Peña, María Carmen, Brugarolas Masllorens, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2016
Materias:
Interesting Images
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979627/
https://www.ncbi.nlm.nih.gov/pubmed/27355848
http://dx.doi.org/10.1097/RLU.0000000000001288
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author Crespo-Jara, Aurora
González Manzano, Ramón
Lopera Sierra, Maribel
Redal Peña, María Carmen
Brugarolas Masllorens, Antonio
author_facet Crespo-Jara, Aurora
González Manzano, Ramón
Lopera Sierra, Maribel
Redal Peña, María Carmen
Brugarolas Masllorens, Antonio
author_sort Crespo-Jara, Aurora
collection PubMed
description We present a sarcoma patient with a tumor reduction of more than 50% in lung metastasis after 2 single courses of the investigational medical product Lutathera ((177)Lu-DOTA0-Tyr3-octreotate). She was resistant to more than 6 lines of therapy including all the available active drugs in soft tissue sarcomas. The high expression of somatostatin receptors was shown by microarrays and Octreoscan. The overall duration of response exceeded 1 year.
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spelling pubmed-49796272016-08-26 A Patient With Metastatic Sarcoma was Successfully Treated With Radiolabeled Somatostatin Analogs Crespo-Jara, Aurora González Manzano, Ramón Lopera Sierra, Maribel Redal Peña, María Carmen Brugarolas Masllorens, Antonio Clin Nucl Med Interesting Images We present a sarcoma patient with a tumor reduction of more than 50% in lung metastasis after 2 single courses of the investigational medical product Lutathera ((177)Lu-DOTA0-Tyr3-octreotate). She was resistant to more than 6 lines of therapy including all the available active drugs in soft tissue sarcomas. The high expression of somatostatin receptors was shown by microarrays and Octreoscan. The overall duration of response exceeded 1 year. Lippincott Williams & Wilkins 2016-09 2016-06-28 /pmc/articles/PMC4979627/ /pubmed/27355848 http://dx.doi.org/10.1097/RLU.0000000000001288 Text en Copyright © 2016 Wolters Kluwer Health, Inc. All rights reserved. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially.
spellingShingle Interesting Images
Crespo-Jara, Aurora
González Manzano, Ramón
Lopera Sierra, Maribel
Redal Peña, María Carmen
Brugarolas Masllorens, Antonio
A Patient With Metastatic Sarcoma was Successfully Treated With Radiolabeled Somatostatin Analogs
title A Patient With Metastatic Sarcoma was Successfully Treated With Radiolabeled Somatostatin Analogs
title_full A Patient With Metastatic Sarcoma was Successfully Treated With Radiolabeled Somatostatin Analogs
title_fullStr A Patient With Metastatic Sarcoma was Successfully Treated With Radiolabeled Somatostatin Analogs
title_full_unstemmed A Patient With Metastatic Sarcoma was Successfully Treated With Radiolabeled Somatostatin Analogs
title_short A Patient With Metastatic Sarcoma was Successfully Treated With Radiolabeled Somatostatin Analogs
title_sort patient with metastatic sarcoma was successfully treated with radiolabeled somatostatin analogs
topic Interesting Images
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979627/
https://www.ncbi.nlm.nih.gov/pubmed/27355848
http://dx.doi.org/10.1097/RLU.0000000000001288
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