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Palladium-catalyzed picolinamide-directed iodination of remote ortho-C−H bonds of arenes: Synthesis of tetrahydroquinolines

A new palladium-catalyzed picolinamide (PA)-directed ortho-iodination reaction of ε-C(sp(2))−H bonds of γ-arylpropylamine substrates is reported. This reaction proceeds selectively with a variety of γ-arylpropylamines bearing strongly electron-donating or withdrawing substituents, complementing our...

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Detalles Bibliográficos
Autores principales:	Nack, William A, Wang, Xinmou, Wang, Bo, He, Gang, Chen, Gong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2016
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979757/ https://www.ncbi.nlm.nih.gov/pubmed/27559375 http://dx.doi.org/10.3762/bjoc.12.119

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