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Synthesis of the C8’-epimeric thymine pyranosyl amino acid core of amipurimycin

The C8’-epimeric pyranosyl amino acid core 2 of amipurimycin was synthesized from D-glucose derived alcohol 3 in 13 steps and 14% overall yield. Thus, the Sharpless asymmetric epoxidation of allyl alcohol 7 followed by trimethyl borate mediated regio-selective oxirane ring opening with azide, afford...

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Detalles Bibliográficos
Autores principales:	Markad, Pramod R, Kumbhar, Navanath, Dhavale, Dilip D
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Beilstein-Institut 2016
Materias:	Full Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4979907/ https://www.ncbi.nlm.nih.gov/pubmed/27559421 http://dx.doi.org/10.3762/bjoc.12.165

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